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Bacterial and Bacteriophage Genetics by Edward A. Birge

By Edward A. Birge

Genetic investigations and manipulations of micro organism and bacteriophage have made important contributions to our easy realizing of dwelling cells and to the advance of molecular biology and biotechnology. This quantity is a survey of the genetics of micro organism and their viruses, and it presents scholars with a entire creation to this quickly altering topic. The publication is written for top point undergraduates and starting graduate scholars, really those that have had an introductory genetics course.

The 5th version has been broadly revised to mirror contemporary advances within the box. The publication now has a reader-friendly glance, with end-of-chapter questions, "Thinking forward" and "Applications" bins to problem scholars’ comprehension and insights. a whole word list of favourite phrases has been revised and multiplied.

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Example text

Indeed, the special term genophore was coined to describe the physical DNA structure of a typical bacterium. However, it is now apparent that there are in fact some 15 1 Fundamentals of Bacterial and Viral Genetics striking parallels between a eukaryotic chromosome and a DNA molecule found in a bacterial cell. John Cairns achieved the first clear visualization of a bacterial DNA molecule, using autoradiography (exposure of a film emulsion by the decay of radioactive atoms) to demonstrate the circularity of an intact tritium-labeled E.

Note that if a symmetric enzyme produces single-strand tails, all of the DNA fragments have identical tails. These single-strand tails can act as “sticky ends” to join various fragments by hydrogen bonding. The same is not true for the asymmetric enzymes, which seem to cut at some distance from the recognition site. , all HgaI fragments have fivebase single-strand tails of nonspecific sequence). Although methylation of bases is protective in the typical restriction system discussed earlier, there are exceptions, which constitute a fourth group of restriction enzymes.

Annual Review of Genetics 21: 23–46. Lydall, D. (2003). Hiding at the ends of yeast chromosomes: Telomeres, nucleases and checkpoint pathways. Journal of Cell Science 116: 4057–4065. , Lory, S. (2005). Microbial Life. N. (2003). Archaeal chromatin and transcription. Molecular Microbiology 48: 587–598. J. (2003). Bacterial chromosome dynamics. Science 301: 780–785. N. (2003). H-NS in Gram-negative bacteria: A family of multifaceted proteins. Trends in Microbiology 11: 511–518. , Sekiguchi, J. (1987).

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