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Advances in the Diagnosis and Treatment of Pancreatic by David C. Whitcomb MD PhD, Adam Slivka MD, Kenneth K. Lee

By David C. Whitcomb MD PhD, Adam Slivka MD, Kenneth K. Lee

Issues of the pancreas have, some time past, been very problematical as the prognosis used to be frequently made past due during the ailment and no considerably necessary interventions have been on hand. this example is quickly altering as new insights from a number of views are built-in and fascinated with each one step of this advanced approaches. This factor of Gastroenterology Clinics of North the US highlights a couple of parts of fast development in inflammatory and neoplastic issues of the pancreas. each one bankruptcy represents the built-in wisdom and point of view of specialists within the box, and signify the freshest research of those cutting-edge methods to advanced concerns within the review and remedy of pancreatic issues.

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Additional resources for Advances in the Diagnosis and Treatment of Pancreatic Diseases, An Issue of Gastroenterology Clinics Vol 36 Issue 2

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Such marked cases of fibrosis and inflammation can result in expansion of the involved area, resulting in a mass that can be described as an ‘‘inflammatory pseudotumor’’ or ‘‘tumefactive’’ AIP; mass lesions of up to 10 cm have been reported [7,61–64]. Another characteristic histologic feature of AIP is venulitis. Inflammatory cells not only surround small- and medium-sized veins, they also infiltrate the walls and the endothelium, which results in an obliterative venulitis (Fig. 4D). The finding of obliterative venulitis, in conjunction with periductal lymphoplasmacytic inflammation, is considered diagnostic of AIP [10].

26] Procacci C, Carbognin G, Biasiutti C, et al. Autoimmune pancreatitis: possibilities of CT characterization. Pancreatology 2001;1(3):246–53. [27] Furukawa N, Muranaka T, Yasumori K, et al. Autoimmune pancreatitis: radiologic findings in three histologically proven cases. J Comput Assist Tomogr 1998;22(6):880–3. [28] Irie H, Honda H, Baba S, et al. Autoimmune pancreatitis: CTand MR characteristics. AJR Am J Roentgenol 1998;170(5):1323–7. [29] Eerens I, Vanbeckevoort D, Vansteenbergen W, et al.

9% when the cannulation was considered difficult, requiring more than 20 attempts [6]. Precut sphincterotomy has also been shown in multiple prospective trials to increase the risk of post-ERCP pancreatitis [2,5,13]. 5% (100 of 2236) in all other patients undergoing ERCP. 3% when done for other indications. The risk for severe pancreatitis was also extremely high in the suspected SOD group, with 25% of patients having a severe course compared with only 2% of patients undergoing precut sphincterotomy for other indications.

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